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What is Colchicine?

Colchicine is a generic medicine, belongs to the family of anti-gout medication. It got approved for medical use in the United States (U.S) in the year 1961. Colchicine is available only with a proper prescription from a doctor, and you can take it orally.

What is the use of Colchicine?

Your doctor can decide to treat you with Colchicine if you have the following health disorder:

  • Gout
  • Familial Mediterranean fever
  • Prevention of pericarditis
  • Any other condition as they determine

Your doctor may prescribe you Colchicine as a part of combination therapy.

Colchicine dosage

Take Colchicine dosage as exactly prescribed by your doctor, and please don’t take it more often than prescribed. Your doctor will recommend Colchicine depending on several factors such as:

  • Your age
  • Your weight
  • Your medical condition
  • Other health disorder you already have
  • How you responded to the first dose of the medicine

Your doctor should prescribe you the lowest possible dose in starting and then gradually increase your medicine dose according to your health condition. To determine a suitable dosage, they should make a full and proper medical checkup of the patient.

The following is the Colchicine usual dose that a doctor can prescribe according to different medical conditions:

Dosage for the treatment of gout

For older adults (65 years and above)

Doctors should be extra careful while prescribing Colchicine dosage to older adults for treating gout.

For adults (more than 18 years but less than 65 years of age)

Initially, 1.2 mg of the medicine followed by 0.6 mg after an hour.

For children (more than 15 years but less than 18 years)

Initially, 1.2 mg of Colchicine tablets followed by 0.6 mg after one hour.

For children (less than 15 years)

Doctors should not recommend Colchicine dosage for the patients of this age group.

Dosage for prevention of gout

For older adults (65 years and above)

Doctors should be extra careful while prescribing Colchicine dosage to older adults for Preventing gout.

For adults (more than 18 years but less than 65 years of age)

0.6 mg of tablet, once or twice a day

For children (more than 15 years but less than 18 years)

0.6 mg of the medicine, once or twice per day

For children (less than 15 years of age)

Doctors should not recommend Colchicine dosage for the patients of this age group.

Dosage for treating familial Mediterranean fever

For older adults (65 years and above)

Doctors should be extra careful while prescribing Colchicine dosage to older adults for treating familial Mediterranean fever.

For adults (more than 18 years but less than 65 years of age)

The usual dose of Colchicine for treating familial Mediterranean fever is 1.2 mg to 2.4 mg of medicine once a day.

For children (more than 12 years but less than 18 years)

The usual Colchicine dosage for this age group is 1.2 mg to 2.4 mg of medicine once a day.

For children (more than six years but less than 11 years)

Initially, 0.9 mg to 1.8 mg of medicine once a day.

For children (more than four years but less than six years)

0.6 mg to 1.8 mg of Colchicine tablets one time a day.

For children (less than three years)

Doctors should not recommend Colchicine dosage for the patients of this age group.

How do Colchicine works?

Colchicine is an anti-gout medication; therefore, it will work similarly to other anti-gout medications work. It decreases the body’s inflammation through various mechanisms, but this medication’s exact working is still a question to be answered.

What to know before using Colchicine?

It is best to keep the following points in mind before using Colchicine:

  • Please don’t take Colchicine without a proper prescription from a doctor.
  • It is best to avoid taking this medication if you are allergic to it or its components or similar medicines.
  • To ensure that taking Colchicine is safe for you, you should tell your doctor if you have or ever had any of the following health disorder:
    • Liver disease
    • Kidney disease
  • It is the patients’ responsibility to say to the doctor about all their current medicines. Their medical professional will prescribe them Colchicine accordingly to avoid interaction between medications. The following medicines may interact with Colchicine or may increase the risk of certain side effects or can make other treatments less effective:
    • Antifungal medications
    • Medicines to treat HIV ADIS
    • Antibiotics medicines
    • Antidepressants
    • Drugs for maintaining cholesterol level in the body
    • heart rhythm medication such as digoxin
    • Heart medications
  • Expecting women should not use Colchicine without their doctor’s advice. Taking this medication while pregnancy may cause congenital disability to their child.
  • It can pass to breast milk and harm the nursing baby; therefore, lactating mothers should not use this medication without consulting their doctor.
  • Colchicine can impair your thinking and reactions and may increase the risks of accidents and severe injuries. Therefore, please avoid getting involved in dangerous activities that demand attention and alertness while you are affected by Colchicine.
  • Don’t eat grapefruit while using Colchicine to avoid harmful interactions between these two.
  • If you ever feel uneasiness or overdose symptoms after taking Colchicine, you should consult your doctor ASAP and ask for medical help.
  • You can also get emergency medical assistance by calling the poison helpline at 1-800-222-1222.
  • Please don’t ever ignore Colchicine overdose symptoms as they can be fatal. The following are some overdose symptoms that one can experience after taking this medication:
    • Diarrhea
    • Nausea or vomiting
    • Pain in the stomach
    • Weak muscles
    • Difficulty in urinating
    • Numbness or tingling in the body
    • Weak pulse rate
    • Slow heart rate
    • Shallow breathing
    • Fainting and unconsciousness
  • It is best to avoid using herbal products, nutritional supplements, and other over the counter medications while using Colchicine.
  • You may require some medical tests to determine whether medicine is working well enough for you.
  • Don’t stop using Colchicine out of sudden without Consulting your doctor; otherwise, you may suffer from the medicine’s unpleasant withdrawal symptoms. Your doctor will gradually decrease your Colchicine dose to avoid the adverse effects of leaving this medication.
  • Keep Colchicine tablets out of the reach of children; they may misuse them by mistake.
  • Store Colchicine tablets at room temperature, away from heat and moisture.
  • After completion of treatment, please ask the chemist near you regarding the proper disposal of leftover medicine.
  • You should ask your doctor about all the necessary precautions that you should take while using this medication.
  • You can also consult your doctor to learn more about the risks and benefits associated with Colchicine.

Colchicine side effects

The common side effects of using Colchicine includes the following:

  • Nausea
  • Vomiting
  • Pain in the stomach
  • Diarrhea

It is evident to experience mild side effects symptoms after using this medication. You can still consult your doctor and ask for medical help if these symptoms bother you so much or are unbearable. You should not take medicine anymore and tell your doctor if you experience any of the following health issues:

  • Pain or weakness in the muscles
  • Numbness or tingliness in the fingers and toes
  • Pale or grey-colored lips or tongue
  • Discolored hands
  • Severe diarrhea
  • Nausea or vomiting
  • Fever
  • Chills
  • Pain in the body
  • Symptoms of flu
  • Easy bruising
  • Unusual bleeding
  • Tiredness
  • Weakness
  • Any other allergic reaction to the medicine

You should also report to your doctor if you ever experience any other side effects, symptoms, or symptoms that are getting even worse.

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